Our approach is to optimise next generation targeted therapeutics for the intravitreal treatment of currently blinding or fatal medical retinal conditions. The unit has developed a complete bench to bedside development pipeline, from high technology discovery work of targeted therapeutics in cell culture systems to unit sponsored clinical trials.
Oculoplastics
The oculofacial plastic surgeons at the Vision Care & Research Centre specialize in cosmetic and reconstructive procedures designed to improve the appearance and function of the eyelids and face, allowing patients to look and feel natural again.
The eyelids and structures around the eyes are critical for vision. Injuries, congenital defects, aging changes and tumors can cause pain, eye damage, vision loss and disfigurement. Changes in the eye's appearance or the loss of an eye can decrease one's ability to interact in social settings and in the workplace.
Along with a variety of cosmetic procedures,our surgeonscan insert implants, reconstruct eyelids and eye sockets, correct eyelid-position abnormalities, remove growths and rebuild critical ocular structures.
· Face and Neck Lift Procedures
· Eyelid Surgery
· Brow Elevation (Browlift)
· Neurotoxins and Fillers
· Chemical Peel
· Microneedling
The faculty of the Division of Ophthalmic Plastic and Reconstructive Surgery are currently engaged in research related to the following areas:
- Volumetric assessment of the eye socket and clinical effects changes as a result of orbital trauma and thyroid eye disease.
- Computer-assisted surgery of the eye socket
- Augmented reality application development for soft-tissue facial reconstruction
- Ophthalmology resident and oculoplastic surgery fellowship education quality improvement and assessment
Vision Science Research
The team predominantly works on epidemiology, aetiology and management of refractive errors, importance and role of optometrists in scientific dispensing of spectacles lenses and frames, effects of lighting on visual perceptions, colorimetric analysis of color vision charts and science of color perception.
Clinical Research
Vision Care & Research Centre, a pioneer in the field of clinical research has a vast experience in various departments of ophthalmology. The areas of interest include development and validation of diagnostic tool for a particular ocular condition, application of artificial intelligence and machine learning in the detection and management of ocular conditions, efficacy of treatment and so on.
Vascular disorders of the Retina and Choroid
Penetrative intraviteal anti-angiogenic gene therapy approaches for sub-RPE choroidal neovascularisation in exudative macular degeneration
Targeted intravitreal gene therapy for diabetic retinopathy
Incidence and prevalence of adeno-associated virus antibodies in the type 1 diabetic population and association with diabetic retinopathy
Circulating miRNA makers of diabetic retinopathy: a 5 year study
Quantifying human clinical markers of diabetic retinal neuropathy
Case controlled clinical trial of systemic erythropoietin treatment of diabetic retinal neuropathy in humans
5 year longitudinal study of serum erythropoietin levels in type 1 diabetic patients with diabetic retinopathy
Ocular Oncololgy, Uveitis and Ocular Genetics
Penetrative intravitreal and subretinal suicide gene therapy for the treatment of uveal melanoma Intravitreal modulated immunotherapy for severe choroidal inflammation
Genetic sequencing and pathogenesis of uveal melanoma
Indian trends in the epidemiology of uveal melanoma